Prof. Gregory S. Martin
James E. Paullin Distinguished Professor of Medicine, Emory University

Biography：
Primary Academic Appointment:

2000 – 2009 Assistant Professor of Medicine, Emory University
2009 – 2014 Associate Professor of Medicine with Tenure, Emory University
2014 – present Professor of Medicine with Tenure, Emory University
2023 – present James E. Paullin Distinguished Professor of Medicine, Emory University

Clinical appointments:

2000 – 2005 Director, Emory University Outpatient Pulmonary Service, Grady Memorial Hospital
2005 – present Director, Medical and Coronary Intensive Care Units, Grady Memorial Hospital
2017 – 2020 Master Clinician, Emory University Department of Medicine
2020 – present Eminent Physician, Emory University School of Medicine

Society of Critical Care Medicine:
Elected Executive Committee, Society of Critical Care Medicine, Secretary 2018 – 2020;
President-Elect 2020 – 2021,
President 2021 – 2022,
Past-President 2022 – 2023

Education:
Bachelor of Science degree
Duke University; Durham, North Carolina
August 1985 – May 1989
Major: Biological Psychology / Neurobiology

Doctor of Medicine degree
Vanderbilt University School of Medicine; Nashville, Tennessee
August 1990 – May 1994

Clinical Investigation Course (Nancy Brown, MD)
Vanderbilt University School of Medicine; Nashville, Tennessee
July 1998

Master of Science in Clinical Research (John Boring, PhD)
Emory University Graduate School of Arts and Sciences; Atlanta, Georgia
August 2002 – May 2004

Dr. Marilyn Novell Bulloch
Pharmacy Practice; Associate Clinical Professor and Director of Strategic Operations
Auburn University Harrison College of Pharmacy and University of Alabama-Birmingham Heersink School of Medicine

Biography：
Marilyn N. Bulloch, Pharm.D. BCPS, FCCM, SPP is an Associate Clinical and the Director of Strategic Operations at the Auburn University Harrison College of Pharmacy and holds Adjunct Associate Professor appointments with the University of Alabama-Birmingham Heersink School of Medicine and University of Alabama College of Community Health Sciences. Dr. Bulloch received her Doctor of Pharmacy degree from Rutgers, University in 2007. She completed her pharmacy practice residency at the University of Alabama- Birmingham Hospital in 2008 and a specialty residency in critical care pharmacy at Charleston Area Medical Center in Charleston, West Virginia in 2009. Additionally, Dr. Bulloch completed a Faculty Scholars Program in geriatrics through the University of Alabama-Birmingham in 2011. Her current practice site is at DCH Regional Medical Center in Tuscaloosa, Alabama. Her research interests include influenza and respiratory viral infections, geriatric pharmacotherapy, alternative substances of abuse, infectious diseases, and acute and critical care pharmacotherapy. Dr. Bulloch has and continues to serves on multiple committees and in leadership positions for many local, state, and national pharmacy and medical organizations. She was inducted as a Fellow of the American College of Critical Care Medicine in 2017. In January 2024, Dr. Bulloch served as co-chair for the Society of Critical Care Medicine s Annual Congress.

The Definition of Pediatric Sepsis has evolved over the years, and the prediction, detection and response
to pediatric sepsis and its consequences for multiple organ failure are extremely important. In this session, we
will review the data and process for development and publication of the Novel Phoenix Pediatric Sepsis
Criteria, using broad registries of data and an artificial intelligence (AI) informed analysis to generate and
validate the published criteria. Note that data from both typical resource rich and global resource constrained
environments were included in the analytic dataset. This unique process of consensus Sepsis definitions and
criteria development for research will be presented and discussed.

Dr. Marilyn Novell Bulloch
Pharmacy Practice; Associate Clinical Professor and Director of Strategic Operations
Auburn University Harrison College of Pharmacy and University of Alabama-Birmingham Heersink School of Medicine

Biography：
Marilyn N. Bulloch, Pharm.D. BCPS, FCCM, SPP is an Associate Clinical and the Director of Strategic Operations at the Auburn University Harrison College of Pharmacy and holds Adjunct Associate Professor appointments with the University of Alabama-Birmingham Heersink School of Medicine and University of Alabama College of Community Health Sciences. Dr. Bulloch received her Doctor of Pharmacy degree from Rutgers, University in 2007. She completed her pharmacy practice residency at the University of Alabama- Birmingham Hospital in 2008 and a specialty residency in critical care pharmacy at Charleston Area Medical Center in Charleston, West Virginia in 2009. Additionally, Dr. Bulloch completed a Faculty Scholars Program in geriatrics through the University of Alabama-Birmingham in 2011. Her current practice site is at DCH Regional Medical Center in Tuscaloosa, Alabama. Her research interests include influenza and respiratory viral infections, geriatric pharmacotherapy, alternative substances of abuse, infectious diseases, and acute and critical care pharmacotherapy. Dr. Bulloch has and continues to serves on multiple committees and in leadership positions for many local, state, and national pharmacy and medical organizations. She was inducted as a Fellow of the American College of Critical Care Medicine in 2017. In January 2024, Dr. Bulloch served as co-chair for the Society of Critical Care Medicine s Annual Congress.

Prof. Gregory S. Martin
James E. Paullin Distinguished Professor of Medicine, Emory University

Biography：
Primary Academic Appointment:

2000 – 2009 Assistant Professor of Medicine, Emory University
2009 – 2014 Associate Professor of Medicine with Tenure, Emory University
2014 – present Professor of Medicine with Tenure, Emory University
2023 – present James E. Paullin Distinguished Professor of Medicine, Emory University

Clinical appointments:

2000 – 2005 Director, Emory University Outpatient Pulmonary Service, Grady Memorial Hospital
2005 – present Director, Medical and Coronary Intensive Care Units, Grady Memorial Hospital
2017 – 2020 Master Clinician, Emory University Department of Medicine
2020 – present Eminent Physician, Emory University School of Medicine

Society of Critical Care Medicine:
Elected Executive Committee, Society of Critical Care Medicine, Secretary 2018 – 2020;
President-Elect 2020 – 2021,
President 2021 – 2022,
Past-President 2022 – 2023

Education:
Bachelor of Science degree
Duke University; Durham, North Carolina
August 1985 – May 1989
Major: Biological Psychology / Neurobiology

Doctor of Medicine degree
Vanderbilt University School of Medicine; Nashville, Tennessee
August 1990 – May 1994

Clinical Investigation Course (Nancy Brown, MD)
Vanderbilt University School of Medicine; Nashville, Tennessee
July 1998

Master of Science in Clinical Research (John Boring, PhD)
Emory University Graduate School of Arts and Sciences; Atlanta, Georgia
August 2002 – May 2004

Prof. Cherylee Wai Jun Chang
Professor, Neurology, Neurosurgery, & Medicine; Division Chief, Neurocritical Care
Duke University
Biography：
Dr. Chang is the Division Chief of Neurocritical Care (NCC) and a Professor of Neurology, Neurosurgery and Medicine at Duke University. She is the current treasurer of the Society of Critical Care Medicine (SCCM) and was an Associate Editor for one of SCCM’s official journals, Critical Care Medicine. Her career has been dedicated to creating pathways for certification of individuals and accreditation of fellowship training programs in NCC. She is member of the American Board of Internal Medicine’s Critical Care Medicine Approval Committee and the American Board of Psychiatry and Neurology’s NCC Examination Committee. Dr. Chang served as the third president of the Neurocritical Care Society from 2007 to 2009 and is a liaison to the NCC Accreditation Committee of the Committee on Advanced Subspecialty Training for the Society of Neurological Surgeons.

She received her bachelor’s degree in Biological Sciences with Honors and Distinction from Stanford University and her medical degree at the University of California, San Diego. She completed residencies in neurology at Stanford University Medical Center and internal medicine at UC San Diego, and joint fellowships in critical care medicine and neurocritical care at the University of Virginia. She is board certified in neurology, critical care medicine and neurocritical care.

This presentation is from the SCCM 2024 Congress that included a review of the most recent literature covering topics in neurocritical care. These included publications regarding acute ischemic stroke (AIS), intracerebral hemorrhage (ICH), subarachnoid hemorrhage (SAH), and subdural hematomas (SDH).

The audience take aways will include: lower blood pressure targets are not necessarily optimal after mechanical thrombectomy for AIS; early recurrent AIS stroke prophylaxis with a direct oral anticoagulant (DOAC) for atrial fibrillation is safe compared to delayed DOAC initiation; intravenous thrombolysis can be safe in AIS patients taking a DOAC; tirofiban may improve outcomes after AIS; bundled goal-directed care after ICH may improve outcomes; drainage of cerebrospinal fluid by lumbar drain after SAH may improve outcomes; evacuation of an acute SDH by craniotomy has similar outcomes compared to decompressive craniectomy; and dexamethasone is not a safe alternative to burr hole evacuation of a chronic SDH.

Ongoing research continues to refine the management of critically ill patients with neurological injuries.

Dr. 王彩融(Tsai-Jung Wang)
Attending Physician, Department of Critical Care Medicine, Attending Physician, Division of Nephrology, Department of Internal Medicine, Taichung Veterans General Hospital, Taiwan
Lecturer, National Yang Ming Chiao Tung University, Taiwan. Clinical Assistant Professor, National Defense Medical Center, Taiwan.

Biography：
EDUCATION
2007 National Yang-Ming University, Taipei, Taiwan
Doctor of Medicine
2020 The University of Texas Health Science Center at Houston, USA
Graduate Certificate Program of Public Health
CLINICAL APPOINTMENT
2020- Attending Physician, Department of Critical Care Medicine,
Attending Physician, Division of Nephrology, Department of Internal Medicine,
Taichung Veterans General Hospital, Taiwan
2016-2018 Attending Physician, Chang-An Clinic, Taiwan
2012-2016 Attending Physician, Division of Nephrology, Department of Internal Medicine, Chiayi
Branch, Taichung Veterans General Hospital, Taiwan
ACADEMIC TEACHING
2022- Lecturer, National Yang Ming Chiao Tung University, Taiwan
Clinical Assistant Professor, National Defense Medical Center, Taiwan
CLINICAL TRAINING
2010-2012 Chief Resident, Medicine, Taichung Veterans General Hospital, Taiwan
2007-2010 Resident, Medicine, Taichung Veterans General Hospital, Taiwan

AWARDS AND HONORS
Best Clinical Research Paper, Hsiu-yang Warm Earth Medical Paper Award, 2024
Best Clinical Research Paper, Taiwan Society of Nephrology, 2023 Annual Meeting
(Title：Machine learning algorithm for early prediction of liberation from dialysis in critically ill adults with
acute kidney injury)
Best Clinical Teacher Award, Taichung Veterans General Hospital, 2022
Author group of Taiwan Chronic Kidney Disease Clinical Guidelines, 2015 and 2022
Best Clinical Research Paper, The Transplantation Society of Taiwan, 2014 Annual Meeting
(Title: Acute Kidney Injury Requiring Dialysis, Mortality, and Risk Factors in Solid Organ Transplant
Recipients)
Finalist in 2014 Taiwan Joint Conference and Annual Conference of Asian Society for Quality in Health Care
(Title: Quality Improvement and Vertical Integration among Healthcare Providers in Hemodialysis)
Best Clinical Teacher Award, Taichung Veterans General Hospital, 2009-2011

CURRENT RESEARCH PROJECTS
Micronutrients deficiency in acute kidney injury
Sepsis associated acute kidney injury

Dr. Leo Anthony Celi
Senior Research Scientist (MIT); Associate Professor (Harvard Medical School)
Massachusetts Institute of Technology; Harvard Medical School
Dr. Celi is the principal investigator behind the Medical Information Mart for Intensive Care (MIMIC) and its offsprings, MIMIC-CXR, MIMIC-ED, MIMIC-ECHO, and MIMIC-ECG. With over 70,000 users worldwide, an open codebase, and close to 10k publications in Google Scholar, the datasets have undoubtedly shaped the course of machine learning in healthcare in the United States and beyond. His group has written 3 open-access textbooks: “Secondary Analysis of Electronic Health Records” in 2016, “Global Health Informatics: Principles of eHealth and mHealth to Improve Quality of Care” in 2017, and “Leveraging Data Science for Global Health” in 2020. The first has been downloaded over 1.7 million times and translated into Mandarin, Spanish, Korean and Portuguese. The group has created two open online courses, “Global Health Informatics' and “Collaborative Data Science for Healthcare”. Finally, in partnership with hospitals, universities and professional societies across the globe, Dr. Celi and his team have organized 45 datathons in 22 countries, bringing together students, clinicians, researchers, and engineers to leverage data routinely collected in the process of care.

We are at the precipice of an artificial intelligence or AI revolution. AI is unique because it is boundless when it comes to applications. It is poised to upend every aspect of our lives, from healthcare, to education, to law enforcement, AI can theoretically augment every human task that involves thinking, and we shall see every decision-making infiltrated by AI. But the biggest difference of AI from other innovations lies in how it is developed. AI is inequitable by design because its raw materials are the digital exhaust of health systems that we know are discriminatory.
AI has the potential to transform critical care medicine worldwide. bearing promises of increased accuracy, efficiency, and cost-effectiveness, in areas as diverse as clinical prediction and prognostication, disease phenotyping, and treatment optimization, among others. But even with high quality data from the intensive care units from across the world, the social patterning of the data generation process can still produce AI that is bound to preserve and even scale existing disparities in care with resulting inequities in patient outcomes. For example, medical devices that measure physiologic signals and biologic markers are developed with subjects that often don’t fully represent those who are most vulnerable to the disease processes in question. Non-random variations in testing and monitoring are bound to adversely affect accurate depictions of disease trajectory in a manner that cannot be compensated for by current imputation methodologies. The promise/hype of AI will translate into huge dividends only if the intensive care community works with computer scientists, social scientists, patients and their caregivers in understanding the backstories of the data and designing an equity-focused curation and analytics pipeline.

Evidence informed Extubation criteria and clinical pathways, and the risks/benefits of extubation readiness
tests for pediatric patients have been debated for many years. The evidence basis, pros and cons, for
extubation readiness testing and clinical pathways will be presented and discussed. Clinical pathway
compliance decrease morbidity, duration of mechanical ventilation and ICU length of stay, but often require
ancillary staffing and support. In addition, special circumstances and unique patient populations may not
benefit to the same extent as the general ICU population. Appropriate evaluation and planning will be
discussed and debated, with welcome input from attendees on their clinical practice and challenges.

Prof. 黃建華(Chien-Hua Huang)
Director, Department of Health,Taipei City Government
Department of Emergency, National Taiwan University Hospital
Dr. Huang got his medical doctor degree in Medical College of National Taiwan University. After completing the residence training of internal medicine and fellowship training of cardiovascular medicine, Dr. Huang received full resident training of emergency medicine in National Taiwan University Hospital. Dr. Huang then entered Graduate Institute of Clinical Medicine and got his doctorate degree. He received a grant supporting post-doctorate research in Baylor College of Medicine in Houston, Texas. His major research interests include acute cardiac care, resuscitation and post-cardiac arrest care including targeted temperature management. Dr. Huang has more than 100 publications including clinical and laboratory studies. He receives awards from the fields of academic research, team work management and administrative works in these years. His recent interests focus on Machine Learning to improve the clinical management of cardiac arrest and post-cardiac arrest syndrome.

Peter Morley
Director of Medical Education
University of Melbourne, Royal Melbourne Hospital, ILCOR
Professor, and Clinical Dean of the Royal Melbourne Hospital Clinical School, for The University of Melbourne, and Senior Specialist, Intensive Care Unit, and Director of Medical Governance at the Royal Melbourne Hospital, Melbourne, Victoria, Australia.
Completed training as Specialist Anaesthetist (1989), Specialist in Intensive Care (1989), Consultant Physician (Jan 1991) and as Associate Fellow of the Royal Australasian College of Medical Administrators (2016).
Over 25 years of involvement in the evidence evaluation process: including for the Australian National Health & Medical Research Council, the Therapeutic Goods Administration, the Australian Resuscitation Council, the National COVID19 Clinical Evidence Taskforce, the International Liaison Committee On Resuscitation [ILCOR], the European Resuscitation Council, and the American Heart Association.
Involvement since 1998 in the development of ILCOR’s international evidence-based guidelines and Consensus on Science and treatment Recommendations as ILCOR representative of Australian and New Zealand Committee on Resuscitation (ANZCOR), task force/subcommittee member, Editorial Board member, and Evidence Evaluation Expert (for 2005, 2010, 2015 recommendations). Currently Chair of ILCOR’s Scientific Advisory Committee (for 2020 recommendations), Chair of Australian Resuscitation Council, and member of the ILCOR Board (Honorary Treasurer)

黃彥達醫師:
2006/9~2011/1 慈濟大學藥理暨毒理學研究所
Institute of pharmacology and toxicology, Tzu Chi University 博士 PhD
2021/1~迄今 成大醫院外科部SICU
SICU, department of surgery, National Cheng Kung University Hospital 主治醫師
Attending physician
2022/8~迄今 成大醫學院外科學科
Department of surgery, college of medicine, National Cheng Kung Univeristy 臨床副教授
Clinical associate professor

This presentation will introduce the selection of intravenous fluids for resuscitation in various critical conditions based on the latest clinical practice guidelines. It will also discuss the pros and cons of different intravenous fluids based on their composition.
議程表:

Dr. Christina Wang received her medical degree from the National Taiwan University Hospital College of Medicine and a master’s degree from the Graduate Institute of Medicine in Yuan Ze University.
She completed her surgical residency at the Far Eastern Memorial Hospital and was trained as a thoracic surgeon. She currently works as an attending physician in the Division of Trauma and part-time in the surgical intensive care unit in the Far Eastern Memorial Hospital. Dr. Wang’s interests include overall general trauma care, thoracic trauma, and rib fracture fixation.

Trauma-related airway difficulties in trauma patients are critical challenges requiring immediate and effective management to ensure survival. These emergencies often stem from direct airway
injuries, cervical spine trauma, or compromised ventilation due to thoracic trauma. Rapid assessment and intervention are crucial, utilizing techniques such as endotracheal intubation, cricothyrotomy, or tracheostomy based on the injury's severity and nature. Advanced airway management protocols and training for healthcare providers are essential to improve outcomes. Continuous monitoring and supportive care in trauma patients are vital to address complications and maintain airway patency throughout the recovery process.

Dr. 廖健宏(Chien-Hung Liao)
Associate Professor,Department of trauma and emergency surgery
Chang Gung Memorial Hospital
Dr. Chien-Hung Liao received his medical degree from Chang Gung University, Taiwan, in 2004 and completed his surgical training at Chang Gung Memorial Hospital. Currently, he serves as a trauma surgeon and professor at the Trauma Center of Chang Gung Memorial Hospital.

His research focuses on enhancing the quality of trauma management and acute care, with a particular emphasis on medical device innovation and the application of digital health technologies for critical patients.

Dr. Liao is also an active member of several international societies and serves on various committees, playing a key role in global trauma care collaboration and fostering international partnerships.

In recent years, Dr. Liao has concentrated his efforts on integrating artificial intelligence (AI) into medical care and developing digital health systems to advance patient outcomes. He has authored over 100 peer-reviewed articles and contributed to multiple textbook chapters in his field.

The integration of deep learning (DL) technologies into trauma care might transform diagnostic and decision-making processes. In this presentation, I will discuss the application of DL models for trauma imaging, including rib fractures, pelvic fractures, abdominal sonography, abdominal computed tomography (CT), and a bleeding prediction model for intensive care unit (ICU) patients.

Our DL models for rib and pelvic fractures, based on X-rays, have demonstrated improved diagnostic accuracy and sensitivity compared to traditional radiological assessments. The DL models can achieve higher accuracy rates in detecting subtle rib fractures, particularly in cases where conventional methods may overlook minor fractures. Similarly, we also highlighted the role of DL in enhancing pelvic fracture detection, reducing misdiagnosis and expediting treatment decisions.

For abdominal trauma, DL-enhanced ultrasonography and CT scanning play a critical role in detecting solid organ injuries, such as liver, spleen or kidney lacerations. The exsting DL algorithms could increase the sensitivity of detecting visceral injuries, even when clinical signs are absent. I also demostrate the feasibility to apply DL model for CT scanning to detect the solid organ injuries.

Moreover, our ICU bleeding prediction model analyzes physiological and laborary data, predicting bleeding risk with a high degree of accuracy. This study demonstrated that AI-driven prediction models significantly reduce mortality by providing early intervention opportunities.

Through these concepts, I will demonstrate how DL models are advancing acute care surgery, leading to improved diagnostic accuracy, expedited decision-making, and optimized patient management in trauma settings

The respiratory management of immunocompromised patients requires selecting appropriate ventilation
strategies based on their specific conditions and risk factors. These patients often have weakened
immune systems due to treatments such as chemotherapy, organ transplantation, or long-term steroid use.
Therefore, when acute respiratory failure (ARF) occurs, it is crucial to choose suitable respiratory support
strategies. The main ventilation strategies include Non-Invasive Ventilation (NIV) and High-Flow Nasal
Cannula (HFNC). NIV is recommended as the first-line treatment for ARF in immunocompromised patients
because it can reduce intubation and mortality rates. However, the application of NIV remains controversial
in some cases, especially when patients exhibit strong inspiratory efforts and high tidal volumes, which may
worsen lung injury.
Studies have shown that when immunocompromised patients require Invasive Mechanical Ventilation (IMV),
the mortality rate can reach 50% to 70%. Early use of NIV can reduce intubation rates and ICU mortality to
some extent, but if the patient's condition is severe and intubation cannot be avoided, delayed intubation may
increase the risk of death. Therefore, early identification of patients who need IMV and timely intubation is
key to avoiding unnecessary delays and high mortality rates.
During the COVID-19 pandemic, managing immunocompromised patients has become more complex,
requiring special consideration of viral infection risks and the choice of respiratory support strategies.
For these patients, selecting the appropriate ventilation strategy is particularly important to minimize
complications and improve survival rates. Overall, ventilation management for immunocompromised
patients requires individualized treatment plans, adjusting respiratory support strategies according to
the patient's condition and risk factors. Early identification and timely intervention are crucial for improving
outcomes. More research is needed in the future to determine the best oxygenation strategies and
management plans to reduce mortality in these high-risk patients.

Dr. 黃虹綾(Hung-Ling Huang)
Associate Professor, Division of Pulmonary and Critical Care Medicine, Department of Internal Medicine, Kaohsiung Medical University Hospital, Kaohsiung, Taiwan
Biography：
I am Hung-Ling Huang, a pulmonologist in Kaohsiung Medical University Hospital and an associate professor of Internal medicine at Kaohsiung Medical University in Taiwan. I am also the director of the Taiwan Society of Tuberculosis and Lung Disease. My research primarily focuses on pulmonary infections, particularly pulmonary tuberculosis, latent tuberculosis infection, nontuberculous mycobacterial pulmonary disease, and pulmonary aspergillosis. In recent years, I have participated in various studies to investigate the role of gut and respiratory microbiota in various pulmonary infectious disease, aiming to identify potential biomarkers for disease progression and novel therapeutic targets. I also have executed many research projects of pulmonary infection as principal investigator and participated in randomized clinical trials and cross-nations studies.

The human body hosts over 10,000 different microbe species, forming complex communities known as microbiota. The aggregate of these microbial species, along with their genetic information and functions, is referred to as the microbiome. Initiated in 2007, the Human Microbiome Project (HMP) aims to enhance our understanding of human–microbe interactions and clarify the mechanisms of host–microbiome interactions under specific conditions. Alterations in microbiomes from different bodily regions can influence human development and lead to abnormal development and disease. Over 90% of diseases can be traced back to microbiota dysbiosis. While the respiratory microbiome has been less explored compared to the gut microbiome, its dysbiosis is speculated to play a significant role in ventilator-associated pneumonia (VAP) and acute respiratory distress syndrome (ARDS). Despite limited studies and small cohorts, there is evidence of overlap between bacterial populations in the lower respiratory and oropharyngeal tracts. A comprehensive understanding of microbial interplay and host-microbiome interactions could guide better preventive and therapeutic strategies for ARDS and VAP. We herein review and summarizes current knowledge and potential clinical applications of respiratory microbiome research in mechanically ventilated patients.

Biography：
Current Position
Attending Physician Jul 1996~ Division of pulmonary and Critical Care
Chief Sep 2001~ Respiratory Care Center
President Apr 2008 ~ Apr 2012 Taiwan Society of Sleep Medicine
Chief Mar 2009 ~ present Sleep Medicine Center
Chief Jun 2009 ~ Nov 2011 Department of Respiratory Therapy, China Medical University
Director 2020~ Taiwan Society of Pulmonary and Critical Care Medicine

Obstruction sleep breathing disorder, obesity
Sleep is a naturally occurring periodic, reversible state of cognitive and sensory disengagement from the external environment, from which a person can be aroused by sensory stimulation. Sleep is essential for physiologic rest and emotional well-being Chemically-induced sedation is physiologically different to normal sleep and lacks restorative effects. Sleep patterns and architecture in the critically ill is usually abnormal. There are multiple causes of disrupted sleep in ICU.
I focus on the complication of sleep breathing disorder and obesity in ICU. Obstructive sleep apnea is common in patients admitted to the ICU. Obstructive sleep apnea was associated with a reduction in both ICU and hospital mortality.
Journal of Critical Care Volume 30, Issue 1. February 2015, Pages 178-18
The prevalence of obesity is increasing worldwide and is around 20% in ICU patients. Obesity is strongly linked with chronic diseases such as type 2 diabetes, hypertension, cardiovascular diseases, dyslipidemia, non-alcoholic fatty liver disease, chronic kidney disease, obstructive sleep apnea and hypoventilation syndrome, mood disorders and physical disabilities. Intensive Care Med (2019) 45:757–769
We analysis the four endotypic traits, namely arousal threshold, upper airway collapsibility, loop gain, and upper airway muscle compensation, were estimated using the PUP method, specifically through a validated cloud-based Python application (PUPpy) (E. Finnsson et al., 2021).
Endotyping has the potential to open novel therapeutic avenues. BiPAP or CPAP is highly efficacious in treating OSA with hypoventilation, regardless of the underlying pathophysiology of OSA. Therefore, endotypes could help choose the personalised alternatives to BiPAP of CPAP. Novel pharmacological therapies targeted at specific endotypes have shown promise but are not yet fully evaluated. thorax-2023-22003

杭良文(Liang-Wen Hang)
Taiwan (台灣)
14:35-14:50
Discussion

Time slot's time in Taipei (GMT+8)
2024/10/5 Room 101 Type: Physical

Dr. 黃道民(Thomas Tao-Min Huang)
Attending Physician/Division of Nephrology, Department of Internal Medicine
National Taiwan University Hospital and College of Medicine
Biography：
Dr. Thomas Tao-Min Huang MD, a distinguished nephrologist, is an Attending Physician in the Department of Internal Medicine (Nephrology Division) at National Taiwan University Hospital (NTUH) and College of Medicine. With his tenure at NTUH starting in 2002 as a Rotation Intern, Dr. Huang has held multiple esteemed positions, including Chief of the Center for Quality Management and the Center for Dialysis at NTUH Yunlin Branch. He also served as a Clinical Lecturer in Internal Medicine.

His academic journey commenced at the Department of Medicine, College of Medicine, NTU, culminating in a series of fellowships in Critical Care Medicine and Nephrology at NTUH. He has been an active member of several professional societies, notably the International Society of Nephrology and the Taiwan Society of Critical Care Medicine.

Dr. Huang’s remarkable contributions to nephrology are evidenced by his multiple awards, including the Young Investigator Fellowship Award from the Asian-Pacific Congress of Hypertension and the Research Award of the Taiwan Society of Nephrology. His excellence in clinical performance and teaching has been consistently recognized, cementing his position as a revered figure in Taiwanese medicine.

Prof. 葉育彰(Tony, Yu-Chang Yeh)
Director
Department of Anesthesiology, National Taiwan University Hospital
Prof. Yu-Chang Yeh is the director of the Department of Anesthesiology, National Taiwan
University Hospital (NTUH). He is the chair of the International Affairs for both the Taiwan
Society of Critical Care Medicine (TSCCM) and the Taiwan Society of Emergency and
Critical Care Medicine (TSECCM). He is the chair of the Critical Care Committee of the
Taiwan Society of Anesthesiologists (TSA). He received his medical degree from the
College of Medicine, Yang-Ming University, Taiwan, in 1998 and PhD from the College of
Medicine, National Taiwan University in 2012. His clinical and research interests include
microcirculation, sepsis, blood purification, extracorporeal life support, therapeutic
sedation and analgesia, delirium, kidney transplant, and data science. He assisted in the
establishment of the NTUH center of microcirculation medical research (NCMMR), NTUH
Smart Emergency and Critical Care group (NSECC), and a national critical care database
(Taiwan CORE). Dr. Yeh authored or co-authored more than 70 peer-reviewed papers
and invited as a speaker more than 170 national and international conferences.

The rapid growth of Generative AI (GAI) is revolutionizing emergency and critical care, offering
unprecedented opportunities and challenges. As GAI technologies, including machine learning
(ML) and large language models (LLMs), advance, they enable more efficient, accurate, and
personalized patient care. In this speech, we will explore the vast potential of GAI in enhancing
diagnostic accuracy, predicting patient outcomes, and optimizing treatment strategies in highstakes
environments.
Opportunities abound in leveraging GAI to improve decision-making processes, streamline
workflows, and enhance the integration of complex data. However, the challenges of deploying
these technologies in clinical settings are equally significant, including ethical considerations,
data privacy, and the need for continuous model validation and fine-tuning.
The transition from traditional ML workflows to LLM-driven approaches will be highlighted,
showcasing how LLMs can refine clinical reasoning through advanced prompting techniques,
Retrieval-Augmented Generation (RAG), and fine-tuning. These methods allow for more
nuanced and context-aware AI-driven support, ultimately improving patient outcomes in
emergency and critical care.
This talk aims to provide a comprehensive overview of GAI's current state, its future in
healthcare, and the practical steps needed to harness its full potential while addressing the
inherent challenges.

Teemo, responsible for the Health Insurance system and certain aspects of the emergency system at National Taiwan University Hospital, across all its branches. My work involves implementing virtual national health insurance cards, ambulance services, and major illness data.
I am also a long-term participant in the g0v community and an alumnus of the Taiwan Artificial Intelligence School. I focus on the development and governance of generative AI in Taiwan. I have a popular series of videos on YouTube that explain the fundamental concepts of artificial intelligence, which has garnered a significant following among viewers.
Over the past year, I've explored the use of generative AI in performance, art, and professional work, achieving notable successes that have gained recognition within the tech community. My experiments with AI across these diverse fields have yielded impressive results, establishing my reputation as an innovative practitioner in the intersection of technology and creative applications.

Key to Seamless Integration: Introducing generative AI into healthcare systems must be painless, reducing resistance and difficulty during the implementation process to ensure smooth adoption.
Generative AI Proposal Criteria: When evaluating a proposal, ask three questions first: Does it improve efficiency? Does it reduce errors? Does it mitigate legal risks?
Limitations and Challenges of generative AI: LLMs (Large Language Models) excel at handling data, but in practical applications, they may produce correct yet impractical outputs. For instance, an anorexic patient’s BMI of 14.8 is an objective fact, but directly recording it in medical notes might negatively impact the patient's emotional state.
Product Demonstration and Application: Medical documents without personal data or privacy-sensitive information are uploaded to the cloud, enabling a chatbot to respond to user inquiries. These tools allow frontline healthcare workers to quickly access accurate information while ensuring patient privacy is protected.
Growth Process of Doctors, Residents, and Medical Students: Effective management of personalized knowledge is crucial. Using tools like Obsidian, medical professionals can convert notes into bi-directional links, creating a knowledge graph that enhances learning outcomes.
Personalized Knowledge Management and Tool Application: Daily handwritten notes from healthcare professionals can be converted into Markdown syntax for use in knowledge management tools, improving work efficiency and knowledge integration.

議程請見附檔.
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口頭論文 競賽-時程請見附檔.
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Vinay Nadkarni MD, MS is a Professor at the Children’s Hospital of Philadelphia (CHOP),
and founding director for the CHOP Academy for Resuscitation of Children, Center for Pediatric
Resuscitation and the CHOP Center for Simulation, Advanced Education and Innovation. Dr.
Nadkarni is an active leader of some of the most influential international societies and organizations
in the field of critical care and resuscitation science: the American Heart Association, ILCOR (the
International Liaison Committee on Resuscitation), WFPICCS (the World Federation of Pediatric
Intensive and Critical Care Societies), and served as the President of the Society of Critical Care
Medicine 2023. Dr. Nadkarni has authored more than 750 peer-reviewed manuscripts and 35 book
chapters related to the practice of critical care. Over the course of his career, he has mentored
more than 150 postdoctoral fellows and physician-scientists, culminating in recognition by the
SCCM Asmund S. Laerdal Award, American Academy of Pediatrics Critical Care Lifetime
Distinguished Career Award, the International Liaison Committee on Resuscitation (ILCOR) Giant’s
award, the AHA Lifetime Achievement Award for Resuscitation Science, the Citizen CPR
Foundation Hans Dahll Award, and the AHA Ron Haddock International Impact Award.

Time critical interventions for life and organ function threatening conditions are crucial for efffective prevention,
respone, and resuscitation. The emerging challenges and controversies in Pediatric Advanced Life Support
and Cardiac Arrrest resuscitation will be presented and discussed. Each phase of resuscitation (prediction,
prevention, recognition, activation, response, post-resuscitation care, rehabilitation, and re-integration to
home and community) will be addressed. Discussion of the application of these novel and emerging
approaches will be tempered by solicitation of contextualized approaches and debate among attendees.

時程附加檔案
議程表:

Prof. Matteo Bassetti
Chief, Infectious Disease Division
Ospedale Policlinico San Martino, Genoa, Italy.

Medical education
1995: Degree in Medicine at University of Genoa School of Medicine, Genoa, Italy
1999: Specialized in Infectious Diseases at University of Genoa School of Medicine, Genoa, Italy
2001: Post-graduate fellowship in Infectious Diseases at Yale University School of Medicine, New Haven CT, USA
2004: PhD in Infectious Diseases in Solid Organ Transplantation and Infectious Diseases at University of Genoa School Medicine, Genoa, Italy

Academic achievements
2001-2011 Contract Professor of Infectious Diseases at University of Genoa School of Medicine and in the Postgraduate Schools of Infectious Diseases, Hematology and Hygiene if the same university
2011- 2016. Contract Professor of Infectious Diseases at University of Udine School of Medicine and in the Postgraduate School of Hygiene, Haematology, Oncology, Critical Care and Anaesthesiology if the same university
2016-2019. Associate-Professor of Infectious Disease, University of Udine
2019-toda. Full-Professor of Infectious Disease, University of Genoa

Role in international groups/scientific societies
2008: Secretary of the Infectious Diseases Group (IDG) of European Organization for Research and Treatment of Cancer (EORTC).
2011-2016 Treasurer and vice-Chair of the “Critically ill study group” of the European Society of Clinical Microbiology and Infectious Diseases (ESCMID)”.
2016-today : Chair of the “Critically ill study group” of the European Society of Clinical Microbiology and Infectious Diseases (ESCMID)”.
2006-2016: Study coordinator for the “Candidiasis Group” of the ESCMID Fungal Infection Study Group.
2009-2016 Secretary of Working Group on Bone and Skin and Soft Tissue Infections (SSTIs) of International Society of Chemotherpy (ISC)
2014-today Co-chair of Working Group on Abdominal infections of International Society of Chemotherpy (ISC)
Elected member and co-chair of the executive committee of the International Society of Chemotherapy (ISC).
2009-2016 Member of the steering committee of the Italian Society of Infectious Diseases
Commission for bone and Joint Infections, skin and soft tissue infections and endocarditis
2013-2019 Vice-President of the Italian Society of Anti-infective Therapy (SITA)
Elected member (2018-2022) of the International Council of the Immunocompromised Host Society (ICHS).
Since 2019, he has been an elected member of the International Sepsis Forum (ISF).
Member of the executive committee of the National Plan for Combating Antimicrobial Resistance- Antimicrobial Resistance (PNCAR) of the Ministry of Health.
Chair of the Infections in the Critical Patient study group of the leading European infectious diseases society, the European Society of Clinical Microbiology and Infectious Diseases (ESCMID/CIP study group).
2019-today President of the Italian Society of Anti-infective Therapy (SITA)
Member of the following societies: Infectious Diseases Society of America (IDSA),
European Society of Clinical Microbiology and Infectious Diseases (ESCMID),
International Society of Infectious Diseases (ISID), Società Italiana di Chemioterapia
(SIC), Società Italiana di Malattie Infettive e Tropicali (SIMIT) e Società Italiana di Terapia Anti-infettiva (SITA).